Protein Modification Reagents
Medchemexpress LLC Pomalidomide-5'-PEG8-C2-COOH | 2138440-78-3 | 98.2% | 697.73 | C32H47N3O14 | 50 MG
Pomalidomide-5'-PEG8-C2-COOH is an E3 ligase ligand-linker conjugate intended as a building block for proteolysis-targeting chimera (PROTAC) synthesis. The molecule combines a pomalidomide-derived warhead with an eight-unit polyethylene glycol (PEG8) spacer and a terminal two-carbon carboxylic acid for coupling, supplied as a high-purity solid for research use.
- Designed for PROTAC construction and E3 ligase engagement.
- Pomalidomide-derived warhead with PEG8 spacer and terminal carboxylic acid for conjugation.
- High reported purity suitable for synthetic applications.
- Soluble in DMSO at high concentration for stock solutions.
- Recommended long-term storage at low temperatures to preserve integrity.
![eMolecules 1146195-72-3 | Fluorescein-PEG2-azide | Broadpharm563.590 | C27H25N5O7S | 96.000 | Oc1ccc2c(Oc3cc(O)ccc3C22OC(=O)c3cc(NC(=S)NCCOCCOCCN=[N+]=[N-])ccc23)c1 | 25mg | 138794144](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC1706638.jpg-250.jpg)
eMolecules 1146195-72-3 | Fluorescein-PEG2-azide | Broadpharm563.590 | C27H25N5O7S | 96.000 | Oc1ccc2c(Oc3cc(O)ccc3C22OC(=O)c3cc(NC(=S)NCCOCCOCCN=[N+]=[N-])ccc23)c1 | 25mg | 138794144
Fluorescein-PEG2-azide | Broadpharm | 1146195-72-3563.590 | C27H25N5O7S | 96.000 | Oc1ccc2c(Oc3cc(O)ccc3C22OC(=O)c3cc(NC(=S)NCCOCCOCCN=[N+]=[N-])ccc23)c1 | 25mg | 138794144
Medchemexpress LLC Propargyl-PEG4-NHS ester | 1428629-70-2 | 97.0% | 357.36 | C16H23NO8 | 1 G
Propargyl-PEG4-NHS ester is an NHS-activated 4-unit polyethylene glycol (PEG) linker bearing a terminal propargyl (alkyne) group used for bioconjugation and click chemistry. It reacts with amine-containing molecules via the NHS ester and enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) for linker installation in antibody-drug conjugates and other bioconjugation workflows. Supplied as a viscous liquid for research use.
- 4-unit PEG linker with terminal alkyne functional group.
- NHS ester provides amine-reactive conjugation chemistry.
- Compatible with copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- High purity (97.0%) suitable for research applications.
- Soluble in DMSO (≈200 mg/mL) and common co-solvent mixtures for in vivo dosing.
- Available in multiple pack sizes, including 1 g.
Medchemexpress LLC Fmoc-NH-PEG3-CH2CH2COOH | 867062-95-1 | MFCD06656471 | 99.8% | 443.49 g/mol | C24H29NO7 | 100 MG
Fmoc-NH-PEG3-CH2CH2COOH is a PEG-based, Fmoc-protected heterobifunctional linker designed for use in antibody-drug conjugate (ADC) and proteolysis-targeting chimera (PROTAC) construction. It features an Fmoc-protected amine and a terminal carboxylic acid that enable standard peptide-coupling and conjugation chemistries.
- Fmoc-protected amine enabling orthogonal deprotection
- Terminal carboxylic acid for amide coupling
- Molecular formula C24H29NO7 and molecular weight 443.49 g/mol
- Cas number 867062-95-1
- Purity 99.8%
- Available in small-scale packages such as 100 MG
- Storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months)
- Suitable for ADC and PROTAC linker synthesis and bioconjugation
Sigma Aldrich Fine Chemicals Biosciences Collagenase from Clostridium histolyticum | 9001-12-1 | MFCD00130830 | 100mg
Collagenase from Clostridium histolyticum | Mol Wt: 68-130 kDa | 9001-12-1 | MFCD00130830 | 100mg
STA PHARMACEUTICAL US LLC DMTr PEG6 amidite | 1 g | CAS 125607-09-2 | MDL MFCD16876143
DMTr PEG6 amidite is a Amidite reagent (Subcategory: Spacer Modifiers) sold by WuXi TIDES. Offered in 1 g. Store at -20 °C. Ships on dry ice. SDS available for reference.
Specifications
- CAS: 125607-09-2
- MDL: MFCD16876143
- InChIKey: ZTCKUVQHKIMCLI-UHFFFAOYSA-N
- Molecular Weight: 784.927761998
- Molecular Formula: C42H61N2O10P
- Purity: ≥95%
- Container Type: 30 mL Glass (28-400)
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 50.1 g
- Commodity Code: 29299090
- Country Of Origin: China
- IUPAC: 1,1-bis(4-methoxyphenyl)-1-phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(OCCOCCOCCOCCOCCOCCOC(C1=CC=C(C=C1)OC)(C2=CC=C(C=C2)OC)C3=CC=CC=C3)OCCC#N)C(C)C)C
Medchemexpress LLC Dspe-peg-biotin, MW 2000 | 385437-57-0 | 99.9% | 25 MG
DSPE-PEG-Biotin, MW 2000 is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker: one for an E3 ubiquitin ligase and the other for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based linker
- Facilitates PROTAC synthesis
- Targets proteins for degradation
- Utilizes the ubiquitin-proteasome system
Medchemexpress LLC 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44-Pentadecaoxahexatetracontan-46-amine | 2745717-94-4 | 99.9% | 691.85 | 50 MG
The m-PEG15-amine is a chemical compound with the molecular formula C31H65NO15 and a molecular weight of 691.85. It is provided as a colorless to light yellow oil with a purity of 99.91%. This product is intended for use as a laboratory chemical and in the manufacture of substances. It is classified as hazardous, causing acute oral toxicity, skin and serious eye irritation, and potential respiratory tract irritation.
- Consistent with structure based on ¹H NMR Spectrum and LCMS
- Harmful if swallowed
- Causes skin irritation
- Causes serious eye irritation
- May cause respiratory irritation
Thermo Scientific Production Chemicals and Services DOE AND INGALLS
NC3897462 KOLLISOLV PEG 600 204KG DRUM